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The details of FoldDB ID: fd0257
Chemical diagram
molecule

Please see the original reference for structure
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Identification
FoldDB ID

fd0257

One Letter code Help Icon Since there is no uniform representation for the non-natural peptides. The one letter code reported here is as it is mentioned in the original article and/or the external database.

Ac-(T)TWE(X)WD(Z)AIA(E)YA(X)RIE(X)LI(Z)AAQ(E)QQ(E)KNE(X)AL(Z)EL-NH2;

Other note

(T)=homo-threonine, (E)=homo-glutamic acid, (X)=(1S,2S)-2-aminocyclopentane-1-carboxylic acid, (Z)=(3S,4R)-4-aminopyrrolidine-3-carboxylic acid

External ID
Reaxys ID

21646328

NCBI Accession

3O43_B

Structural Information
Structure reported

yes

Method

X-ray

PDB ID

3O43

Reference

fdart0031

Other information
Application

gp41-5 binder

Foldamer type

α/β Peptide

Structure Type

Helical

Activity
Activity ID Assay name Cell line Target Protein Organism Assay Category Value Unit Type Measurement object
fdact0001

Fluorescence Polarization (FP) Competition Assay

gp41

< 9

nM

Ki

Citations
ID Title Year Authors Journal DOI

fdart0031

Broad distribution of energetically important contacts across an extended protein interface

2011

Johnson L.M., Horne W.S., Gellman S.H.

Journal of the American Chemical Society

..