The details of FoldDB ID: fd0354 |
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| Identification | |
|---|---|
| FoldDB ID | fd0354 |
| Three Letter code
Since there is no uniform representation for the non-natural peptides. The three letter code reported here is as it is mentioned in the original article and/or the external database. | (L-Ala-D-Oxd)6-L-Ala-P-RB hydrochloride |
| Smiles | |
| Inchi Key | JCCVSZZPIIUZTH-ZTQYASHGSA-N |
| Molecular weight | 1843.75 |
| Molecular formula | C83H104N17O27*ClH*Cl |
| Source | synthetic construct |
| External ID | |
|---|---|
| Reaxys ID | 30798808 |
| Other information | |
|---|---|
| Application | Bio-comaptible material |
| Foldamer type | α Peptide |
| Structure Type | Helical |
| Activity |
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| Activity ID | Assay name | Cell line | Target Protein | Organism | Assay Category | Value | Unit | Type | Measurement object |
|---|---|---|---|---|---|---|---|---|---|
| fdact0530 | lymphocyte | human | Metabolism/Transport | Low | % uptake | ||||
| fdact0531 | granulocyte | human | Metabolism/Transport | High | % uptake | ||||
| fdact0532 | granulocyte | human | Metabolism/Transport | High | % uptake | ||||
| fdact0533 | monocyte | human | Metabolism/Transport | High | % uptake | ||||
| fdact0534 | HeLa cell line | Metabolism/Transport | Low | % uptake | |||||
| fdact0535 | lymphocyte | human | Metabolism/Transport | Low | % uptake | ||||
| fdact0536 | monocyte | human | Metabolism/Transport | High | % uptake | ||||
| fdact0537 | HeLa cell line | Metabolism/Transport | Low | % uptake | |||||
| fdact0538 | monocyte | human | In Vitro (Efficacy) | High | qualitative | cytosolic distribution |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
Form Matters: Stable Helical Foldamers Preferentially Target Human Monocytes and Granulocytes | 2017 | Del Secco B., Malachin G., Milli L., Zanna N., Papini E., Cornia A., Tavano R., Tomasini C. | ChemMedChem | ||
