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The details of FoldDB ID: fd0354
Chemical diagram
molecule
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Identification
FoldDB ID

fd0354

Three Letter code Help Icon Since there is no uniform representation for the non-natural peptides. The three letter code reported here is as it is mentioned in the original article and/or the external database.

(L-Ala-D-Oxd)6-L-Ala-P-RB hydrochloride

Smiles
Inchi Key

JCCVSZZPIIUZTH-ZTQYASHGSA-N

Molecular weight

1843.75

Molecular formula

C83H104N17O27*ClH*Cl

Source

synthetic construct

External ID
Reaxys ID

30798808

Other information
Application

Bio-comaptible material

Foldamer type

α Peptide

Structure Type

Helical

Activity
Activity ID Assay name Cell line Target Protein Organism Assay Category Value Unit Type Measurement object
fdact0530

lymphocyte

human

Metabolism/Transport

Low

% uptake

fdact0531

granulocyte

human

Metabolism/Transport

High

% uptake

fdact0532

granulocyte

human

Metabolism/Transport

High

% uptake

fdact0533

monocyte

human

Metabolism/Transport

High

% uptake

fdact0534

HeLa cell line

Metabolism/Transport

Low

% uptake

fdact0535

lymphocyte

human

Metabolism/Transport

Low

% uptake

fdact0536

monocyte

human

Metabolism/Transport

High

% uptake

fdact0537

HeLa cell line

Metabolism/Transport

Low

% uptake

fdact0538

monocyte

human

In Vitro (Efficacy)

High

qualitative

cytosolic distribution

Citations
ID Title Year Authors Journal DOI

fdart0039

Form Matters: Stable Helical Foldamers Preferentially Target Human Monocytes and Granulocytes

2017

Del Secco B., Malachin G., Milli L., Zanna N., Papini E., Cornia A., Tavano R., Tomasini C.

ChemMedChem

..