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The details of FoldDB ID: fd0672
Chemical diagram
molecule

Please see the original reference for structure
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Identification
FoldDB ID

fd0672

One Letter code Help Icon Since there is no uniform representation for the non-natural peptides. The one letter code reported here is as it is mentioned in the original article and/or the external database.

VβEPNCDIHV[nL]WβEWECFZRβL-NH2

Note

nL=norleucine

Other note

Z=3-amino-4-carboxypyrrolidin-1-ium, βX=Beta amino acid, disulfide link between the two Cys residues

Source

synthetic construct

Structural Information
Structure reported

No

Other information
Application

VEGF (Vascular Endothelial Growth Factor) signaling inhibitor

Foldamer type

α/β Peptide

Activity
Activity ID Assay name Cell line Target Protein Organism Assay Category Value Unit Type Measurement object
fdact0794

competitive FP assay

In Vitro (Efficacy)

0.74

µM

Ki

Citations
ID Title Year Authors Journal DOI

fdart0091

Extending Foldamer Design beyond α-Helix Mimicry: α/β-Peptide Inhibitors of Vascular Endothelial Growth Factor Signaling

2012

Haase, Holly S., Peterson-Kaufman, Kimberly J., Lan Levengood, Sheeny K., Checco, James W., Murphy, William L., Gellman, Samuel H.

Journal of the American Chemical Society

..