Foldamers are chemical oligomers that mimic the structural behavior of natural peptides, and proteins by folding into well-defined 3D conformation in solution. FoldamerDB is the first public database of peptidic foldamers, created with the aim to gather and provide information related to their identification, experimental structure and biological activities. Links to databases like PDB, CCDC, PubMed, and NCBI are included for the benefit of users.
FoldamerDB is designed to be user-friendly, with options to browse all the foldamers, or browse by articles, or browse structures, or browse foldamers with biological activity. It also allows the user to perform a simple, advanced search as well as chemical fingerprint based sub-structure search.
Bilal Nizami et al., FoldamerDB: a database of peptidic foldamers, Nucleic Acids Research, 2019
Bilal Nizami, Dorottya Bereczki-Szakál, Nikolett Varró, Kamal el Battioui, Vignesh U Nagaraj, Imola Cs Szigyártó, István Mándity, Tamás Beke-Somfai, FoldamerDB: a database of peptidic foldamers, Nucleic Acids Research, 2019
FoldamerDB is best viewed with latest version of Google Chrome and Mozilla Firefox.