The details of FoldDB ID: fd0415 |
|---|
Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.
3D model is for representation purpose only. To access the experimental 3D structure kindly go to the browse structure tab and look for PDB or CCDC id.
.
.
| Identification | |
|---|---|
| FoldDB ID | fd0415 |
| Smiles | |
| Inchi Key | HAVZSVVNZXKXTK-GQNDRTEWSA-N |
| Molecular weight | 1433.77 |
| Molecular formula | C68H108N26O9 |
| Source | synthetic construct |
| External ID | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reaxys ID | 30269876 | ||||||||
| Structural Information | |
|---|---|
| Structure reported | yes |
| Method | NMR |
| NMR Solvent | CD3OH |
| Other information | |
|---|---|
| Application | cell penetrating peptide |
| Foldamer type | Others |
| Other type | Urea-based amino acid |
| Activity |
|---|
| Activity ID | Assay name | Cell line | Target Protein | Organism | Assay Category | Value | Unit | Type | Measurement object |
|---|---|---|---|---|---|---|---|---|---|
| fdact0131 | luciferase expression | HEK293 human cell line |
| qualitative | |||||
| fdact0138 | Gel-shift assay |
| qualitative | ||||||
| fdact0145 | MTT assay | MRC5-V2 |
| qualitative |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
A Cell-Penetrating Foldamer with a Bioreducible Linkage for Intracellular Delivery of DNA | 2015 | Douat Céline,. Aisenbrey Christopher., Antunes Stéphanie., Decossas Marion., Lambert Olivier., Bechinger Burkhard., Kichler Antoine., Guichard Gilles., | Angewandte Chemie - International Edition | ||
