FoldDB_logo

View Foldamer's details


The details of FoldDB ID: fd0421
Chemical diagram
molecule
3D viewer Help Icon Use the buttons at the bottom of Jsmol viewer to see different representations, ON/OFF Hydrogens, and ON/OFF rotation.

3D model is for representation purpose only. To access the experimental 3D structure kindly go to the browse structure tab and look for PDB or CCDC id.

Identification
FoldDB ID

fd0421

Smiles
Inchi Key

BQQHFQVYRLWCJK-FLWZWILHSA-N

Molecular weight

2901.61

Molecular formula

C134H210N52O18S2

Source

synthetic construct

External ID
Reaxys ID

30269884

Structural Information
Structure reported

yes

Method

NMR

NMR Solvent

CD3OH

Other information
Application

cell penetrating peptide

Foldamer type

Others

Other type

Urea-based amino acid

Activity
Activity ID Assay name Cell line Target Protein Organism Assay Category Value Unit Type Measurement object
fdact0137

luciferase expression

HEK293 human cell line

qualitative

fdact0144

Gel-shift assay

qualitative

fdact0151

MTT assay

MRC5-V2

qualitative

Citations
ID Title Year Authors Journal DOI

fdart0049

A Cell-Penetrating Foldamer with a Bioreducible Linkage for Intracellular Delivery of DNA

2015

Douat Céline,. Aisenbrey Christopher., Antunes Stéphanie., Decossas Marion., Lambert Olivier., Bechinger Burkhard., Kichler Antoine., Guichard Gilles.,

Angewandte Chemie - International Edition

..