The details of FoldDB ID: fd0768 |
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| Identification | |
|---|---|
| FoldDB ID | fd0768 |
| Smiles | |
| Inchi Key | BRAHCEVXYCDBCM-UHFFFAOYSA-N |
| Molecular weight | 1104.36 |
| Molecular formula | C58H81N13O9 |
| Source | synthetic construct |
| External ID | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Reaxys ID | 25458110 | ||||||||
| Structural Information | |
|---|---|
| Structure reported | No |
| Other information | |
|---|---|
| Application | antimicrobial activity |
| Foldamer type | Peptoid |
| Calculated properties | |
|---|---|
| LogP | -1.12800 |
| Rotatable Bonds | 44 |
| H Bond Donor | 5 |
| H Bond Acceptor | 22 |
| Polar Surface Area (PSA) | 309.65000 |
| Activity |
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| Activity ID | Assay name | Cell line | Target Protein | Organism | Assay Category | Value | Unit | Type | Measurement object |
|---|---|---|---|---|---|---|---|---|---|
| fdact0237 | Antimicrobial | Bacillus subtilis subsp. spizizenii ATCC 6633 | In Vitro (Efficacy) | 31.3 | μg/mL | MIC | Minimum Inhibitory Concentration | ||
| fdact0238 | Antimicrobial | Escherichia coli ATCC 25922 | In Vitro (Efficacy) | 250 | μg/mL | MIC | Minimum Inhibitory Concentration | ||
| fdact0239 | erythrocyte | human | In Vitro (Efficacy) |
| qualitative | Amount Of Hemoglobin Released | |||
| fdact0240 | Hemolytic | erythrocyte | human | In Vitro (Efficacy) | > 250 | μg/mL | HC10 | Amount Of Hemoglobin Released | |
| fdact0241 | Antimicrobial | Staphylococcus aureus subsp. aureus ATCC 25923 | In Vitro (Efficacy) | 250 | μg/mL | MIC | Minimum Inhibitory Concentration | ||
| fdact0242 | Hemolytic | erythrocyte | human | In Vitro (Efficacy) | > 250 | μg/mL | HC50 | Amount Of Hemoglobin Released |
| Citations | |||||
|---|---|---|---|---|---|
| ID | Title | Year | Authors | Journal | DOI |
A Comparison of Linear and Cyclic Peptoid Oligomers as Potent Antimicrobial Agents | 2012 | Huang, Mia Lace., Shin, Sung Bin Y., Benson, Meredith A., Torres, Victor J., Kirshenbaum, Kent | ChemMedChem | ||
